Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful, young woman with unsightly elf-like bumps on her ears. Jose never goes out because of the baseball-sized lump on his head. Ken is covered in painful bumps that make it difficult to do everyday things.

Barbara's back lump became more noticeable after she lost 131 pounds. Bob has two painful bumps on his back. Hilda's depression is a result of the multitude of bumps on her eyelids. Art has one big bump on his head that he covers up with hats.