Melissa has tried to cover a huge lipoma with a sweatshirt for years, Tyler's fear of cancer has kept him from having his huge head lumps diagnosed, Tahj is covered in painful boils, and Amber has ear keloids that have taken control of her life.

Ronen's mysterious lump above his knee is one of the largest Dr. Lee has ever seen. Amber suffers from a debilitating skin disease that no one understands. Sandy has a neck lump she calls Tommy. Kristy's eyelid cyst is ruining her life.

Half of Mary's body is a size 18 while the other is an 8. Anthony's cyst is in the area called the Triangle of Death. Shane wants to get a lump off his back. Will Brandi's anxiety keep her from getting a lump removed from her chest?