A crossover episode with the cast of "Family Affair". Mr. French, Cissy, Buffy, and Jody's trip to Nairobi is interrupted when Interpol officers at Rome Airport, mistaking Mr. French for a jewel thief, detain them. Mike Endicott (John Forsythe) intervenes, only to be implicated as Mr. French's accomplice.

Paolo, a mute boy who lives abandoned in the streets, is taken by Penny to the house of the Endicotts. After bathing him, dressing him and feeding him, the boy continues to be sullen and surly.

Uncle Charley, Robbie, and Katie from "My Three Sons" visit Rome and the Endicotts. Uncle Charley enlists Mike's help in finding a girlfriend from World War I, while Robbie and Katie hope to enjoy a second honeymoon.