After the disappearance of his wife Valérie, the cosmetic surgeon Pierre Clément went to the criminal section to report this disappearance. Savigny and Revel are put on the investigation and begin by questioning Valérie's sister, Juliette. It does not take long to reveal to investigators that her brother-in-law is not what one can call a model husband ...

Alerted by an intern, Savigny and Revel investigate three strange deaths. Suspecting at first an "angel of death", the investigators review their copies when they discover that it is about a traffic of capsules. They seek to corner the criminal by all means to avoid a cataclysm in the French public health system ...

Benoît Bouvier died mutilated in the room of a large Parisian hotel. During their investigation, Revel and Savigny discover that he had a relationship with a woman whose husband he had defrauded, as well as another couple. The latter would then have ordered the murder for revenge ...