Biz Markie's got a (song about) disease, Xzibit talks "chick flicks", and Cheech & Chong discuss "who's highest". A paramedic and a small business owner must choose between "Yeezus or Jesus", and the winner gets a chance to play for 50K.

Steeler Antonio Brown talks "premarital sacks", Ice Cube gets "hangry", Bill Nye and G-Eazy go on a "nature trip". Snoop Dogg talks real dogs, the "Fairy Doggfather" stops by, and a yoga instructor and professor get their puzzles "pimped".

Steeler Antonio Brown shows off his footwork and Wiz Khalifa does "joint reading". Snoop takes a former Marine and an insurance agent on a journey to "The Highlight Zone" and tells them what "sounds about white". Winner plays for 50K.