To prevent Jazz from developing as a man, the Jennings head to California to replace her expired hormone blocker; Jazz's grandmother confronts some old friends about their feelings on Jazz's transition.

Jazz gets her testosterone blocker replaced, but complications arise that could have disastrous effects on her transition; Jeanette and Jazz go apply for Jazz's driver's permit, and try to have her gender changed to female.

Jazz goes on a radio show but is met with one hateful call after another. Later, Jazz learns shocking details about transitioning at a transgender support group; and the family plans a surprise party for Jeanette's 50th birthday.