When football defensive end Mike unveils his undersized package, Dr. Crawford has to deliver some tough news. Meanwhile, Dr. Baron undertakes an important surgery for her first ever transgender patient Vladimere. Shay visits Dr. Jones with her boyfriend, in the hope that she can rid herself of the trash bags she uses as cover-up and rejuvenate her relationship with the body she has always dreamt of.

Dr. Baron takes on subdued patient Danielle whose life has left her in need of physical and emotional upgrades, but a simple operation could be the key to her future happiness. Dr. Jones meets Sasha, an outrageous personality with a medical secret that threatens to put her life at risk. Ken, a charming aspiring actor goes to see Dr. Crawford for a full body lift after years of dedication and over a hundred pounds of weight loss have left him with excess skin that holds him back from entering the dating scene.

This week, Doctors Crawford and Baron are on opposite sides of the spectrum as Dr. Crawford takes on Mimi, a patient in need of a major breast reduction while his partner Dr. Baron works to enhance the chest of outrageous internet transgender sensation Sidney Favors. Meanwhile, Dr. Jones faces more serious issues when he has to make a tough decision on whether or not to operate on Twanna, a patient whose black market procedures have left her butt disfigured.