The Patriots meet Trump without Brady & O'Reilly meets the Pope without a job. Aubrey Plaza stops by to FaceTime Chelsea Peretti for baby gift ideas.

Desus & Mero celebrate 420 by debating who the hottest white male celebrity is. Shane Smith talks about his Picasso plate and being banned from North Korea.

Obama speaks to Chicago youth about leadership while our nation's leader sends a flurry of angry tweets from his toilet. A$AP Ferg talks fashion & Timb etiquette.