Gazoo convinces Fred to do a Monopoly game with Wilma to spice up their relationship for "togetherness" in their marriage, but things make a turn for the worse when they begin to fight, and Fred decides to stay with Barney, and Wilma stays with Betty until they can make up.

When Fred's allergies become so extreme that he sneezes a hole in the TV screen, Fred decides to take medicine pills called "Scram" from a store which has the disastrous side effect of turning into an ape.

After Fred criticizes a novel about the future that Barney is reading, The Great Gazoo sends Fred, Barney, Betty, and Wilma into the 21st century.