When a young girl was diagnosed with sun poisoning, it completely changed her life and that of her family. She is unable to go outside without first completely covering her body with a long-sleeved shirt, long pants, hat and gloves. Since the sun can also penetrate her clothing, she must apply full body sunscreen every two hours. With the combined effort from the team of designers, contractors, hundreds of workers and state-of-the-art technology, "Extreme Makeover: Home Edition" created a new living space that will enhance the quality of her life while making her living conditions much less restrictive.

After their infant daughter received a heart transplant to save her from the same condition that their son died of as a newborn, Cathy and Bill Grinnan made a promise that they would do whatever they could to educate others about heart disease. Despite their personal tragedies, the Grinnan family became crusaders for heart disease research and treatment. Now it's time for someone to give back to them.

For the past 25 years, Consuela Mackey has tirelessly helped those living with disabilities by providing them with job training, individualized training in personal care and education on workplace etiquette. Since she has devoted most of her life to helping others, it was long overdue for something extremely nice to be done for her. When the team from "Extreme Makeover: Home Edition" came to Consuela's house in Granada Hills, California, they were able to give something back to an individual who has sacrificed so much for her community.