Faced with an impossible work deadline on the night of his Dad's Committee Night Out, Andy takes stimulants. Jill and Vanessa learn the cruel definition of Med Spa as they visit their college friend Ollie at his new venture, Üth.

By day, Jill shoots Brooke's new line of Von Weber wares, and by night she and Vanessa investigate a rash of infections plaguing the Upper "Yeast" Side. Candace seeks answers for why she keeps getting called "Candy Ass," and Lex tries to make the cut at MarsX.

Jill books a photo shoot in Los Angeles and brings Vanessa along. They follow Dave Navarro (playing himself) on a crazy adventure. Meanwhile, Candace oversteps her boundaries with Hazel, and Lex faces his deepest fears in a zero-gravity chamber.