Stars of Match of the Day Kickabout, Tyler West, Rachel Stringer and John Farnworth, take on two young teams in a mash-up of science, entertainment and insanity. In this show, Guinea Pig tries to make a big splash with some genius inventions.

Matilda Ramsay and her twin siblings Jack and Holly are the celebrity team this time. Across six rounds, the teams go up against each other in a test of science knowledge, invention and creativity.

Science monkey superhero Dr Brain pits children and CBBC celebrities against one another in a series of science-based tasks and conundrums designed to discover the 'ultimate brain'.