While attending a medical conference, Rush and Alex plan a guys' weekend. Rush bumps into his ex and treats a politician. Eve tries to start again with Lucas.

Rush is introduced to a powerful hallucinogen that changes his perspective entirely. Alex gets a glimpse of Rush's lifestyle. Eve becomes concerned after belongings disappear from her apartment.

Rush is not pleased when he learns that Sarah has changed. Eve has some time with Manny and Alex maybe in too deep.