After a series of fortunate events that prevented Bob's death, Bob is convinced that his role as God's messenger has granted him the gift of invincibility. All the while, the Devil is frustrated because God never has time for him anymore and he feels that he is being ignored, which once again causes the Devil and Bob's paths to cross.

Bob finds himself put into a mental institute after his behavior while performing a task for god raises questions about his health. With Bob out of the way, the Devil decides to try to seduce his wife in order to mess with Bob even more, but will Bob be able to prove that he's not insane before the Devil's plan succeeds?

God is feeling lonely because he doesn't really have much of a social life due to being God so he decides to try to live life as a human being, in which he gets a job as an auto worker at the plant where Bob works.