Imagine if your ribs and spine were malformed and your organs squashed in a tiny torso? What if you might not survive infancy? Tiffany, 30, and Yajaira, 27, have Jarcho Levin Syndrome. Can meeting bring friendship and answers to lifelong questions?

Imagine if one side of your face didn't form properly? Born with Goldenhar Syndrome, Austin, 15, and Elena, 12, have both been bullied for looking different and feel isolated from other kids. Will meeting bring them the friendship they crave?

Imagine living with a rare and painful condition where your skin grows in thick scales. Bobbi, 49, and Kenny, 45, have Lamellar Ichthyosis. They travel across the USA to meet for the first time, and begin a life-changing friendship.