Boys Giovanni and Owen share the rare condition Schwartz Jampel Syndrome, which permanently and painfully contracts their muscles; the two share hardships and triumphs, and strike up a friendship.

Imagine if your ribs and spine were malformed and your organs squashed in a tiny torso? What if you might not survive infancy? Tiffany, 30, and Yajaira, 27, have Jarcho Levin Syndrome. Can meeting bring friendship and answers to lifelong questions?

Imagine if one side of your face didn't form properly? Born with Goldenhar Syndrome, Austin, 15, and Elena, 12, have both been bullied for looking different and feel isolated from other kids. Will meeting bring them the friendship they crave?