After losing 350 lbs, Melanie wants to just feel normal and date but her layers of skin are in the way. Lauren, once over 400 lbs and now 158 lbs, is so uncomfortable in her excess skin that she cannot have the normal life she wants with her boyfriend.

Mikki became a fitness fanatic, but the weight loss left her with a lot of sagging skin. Denise's sagging skin still hinders her from fitting in with her outgoing family.

Rebecca lost weight to be more active with her young son, but the plan backfired because she is now trapped in her excess skin. After his dad died, Sal lost a lot of weight, but with all the excess skin, he fears he will never become a dad.