After being a victim of a horrible crime, Marranda found solace in food and her weight ballooned. She lost the weight, but the skin is a cruel reminder of her trauma. Jannet's excess skin is keeping her from meeting a life partner.

Rafael lost over 500-lbs through diet & exercise, but now his excess skin is a huge hindrance on his life & progress. Anna lost 330-lbs, but her low self-esteem is holding her back from being the mother she wants to be. Can skin removal surgery help?

Carlynda needs two full knee replacements but doctors won't perform surgery until the skin is gone. After extreme weight loss and marrying the love of her life, Karen is ready start a family but her excess skin is in her way.