Holly lost 200 pounds after a life of abuse, but now excess skin keeps her from the wedding of her dreams; a health scare could affect Mark's upcoming skin removal surgery.

A woman who lost 260 pounds is in danger of also losing her marriage, while a woman who dropped 180 pounds has so much loose skin it's affecting her relationship with her daughters.

A woman reached 512 pounds after her husband suddenly passed away, but now her excess skin hides her dramatic weight loss; a woman lost 191 pounds, but her excess skin is a constant reminder of her obesity and how it damaged her marriage.