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A medical thriller drama set in the world of neurosurgery. A family of surgeons with complicated ties perch at the top of the hospital hierarchy, with son Cha Yeo Wook deciding to follow in his parents' footsteps by becoming a neurosurgeon. Lee Hae Jo is a talented intern who joins the department despite having a less priviledged background than Yeo Wook, and the two develop a bickering friendship while the mysterious doctor Kang Eun Hyun also shows an interest in Hae Jo.